検索結果

Search Results for " collagen 3 "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T9138	Indirubin-3′-oxime	Indirubin-3'-monoxime	GSK-3 , CDK , JNK
	Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.		GSK-3 , CDK , JNK
T16886	Sinefungin	Adenosyl-Ornithine,A-9145,Antibiotic 32232RP	Others , Histone Methyltransferase , Antibiotic , Antifungal
	Sinefungin (Adenosyl-Ornithine) is an effective inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. Sinefungin is a SET7/9 inhibitor and ameliorates r...
TP2362	Acetyl decapeptide-3	Rejuline,Ac-tyr-arg-ser-arg-lys-tyr-thr-ser-trp-tyr-NH2
	Acetyl decapeptide-3 is a peptide that can stimulate collagen and elastin to increase skin elasticity and increase cell growth and improve healing and repair.
T60303	Collagen-IN-1
	Collagen-IN-1 (compound 3) is an ortho-carbonyl hydroquinone derivative exhibiting selective inhibition of collagen. It non-competitively inhibits agonist-induced platelet aggregation, with an IC50 value of 1.77 μM. Coll...
T61811	GPVI antagonist 3
	GPVI antagonist 3 (Compound 2) is a potential antagonist that shows promising antiplatelet activity by selectively inhibiting the interaction between the Glycoprotein VI (GPVI) receptor and its ligands. It demonstrates p...
T36929	Pal-KTTKS (acetate)
	Pal-KTTKS is a lipidated pentapeptide consisting of a fragment of the type I collagen C-terminal propeptide conjugated to palmitic acid .1 It increases collagen production in human corneal and dermal fibroblasts when use...
T82780	Caprooyl-tetrapeptide-3 acetate
	Caprooyl-tetrapeptide-3 acetate, employed for diminishing fine lines and wrinkles, enhances collagen VII and laminin-5 expression in corticoid-induced skin aging models [1].
T12585L	PXS-5153A monohydrochloride	PXS-5153A monohydrochloride (2125956-82-1 free base)	Others
	PXS-5153A monohydrochloride is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC 50 of <40 nM for LOXL2 across all mammalian species and an IC 50 of 6...		Others
T41079	MMP13-IN-2	MMP13-IN-2
	MMP13-IN-2 is a highly potent, selective, and orally active inhibitor of MMP-13. It demonstrates exceptional potency against MMP-13, with an IC50 value of 0.036 nM, and exhibits selectivities greater than 1,500-fold over...
T36101	Psychotridine
	Psychotridine is an alkaloid that has been found inP. forsterianaand has diverse biological activities.1,2,3It inhibits ADP-, collagen-, or thrombin-induced aggregation of washed isolated human platelets with IC50values ...
T38363	MeOSuc-AAPV-pNA
	Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neut...
T81592	Osteostatin	PTHrP (107–111)
	Osteostatin, derived from parathyroid hormone-related protein (PTHrP) 107-111, has demonstrated properties conducive to bone repair in animal models presenting with bone defects and exhibits efficacy in mitigating bone e...
T35695	Oleic Acid-13C
	Oleic acid-13C is intended for use as an internal standard for the quantification of oleic acid by GC- or LC-MS. Oleic acid is a monounsaturated fatty acid and a major component of membrane phospholipids that has been fo...
T74142	Angiotensin II human TFA
	Angiotensin II human TFA, a potent vasoconstrictor within the renin/angiotensin system, plays a pivotal role in human blood pressure regulation primarily through interactions with the G-protein-coupled receptors Angioten...
T36717	RWJ-56110 dihydrochloride
	RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4. RWJ-56110 dihydrochloride inhibits...

Compounds

Indirubin-3′-oxime

T9138

Synonym: Indirubin-3'-monoxime

Target: GSK-3, CDK, JNK

Sinefungin

T16886

Synonym: Adenosyl-Ornithine,A-9145,Antibiotic 32232RP

Target: Others, Histone Methyltransferase, Antibiotic, Antifungal

Acetyl decapeptide-3

TP2362

Synonym: Rejuline,Ac-tyr-arg-ser-arg-lys-tyr-thr-ser-trp-tyr-NH2

Caprooyl-tetrapeptide-3 acetate

T82780

Synonym:

Target:

PXS-5153A monohydrochloride

T12585L

Synonym: PXS-5153A monohydrochloride (2125956-82-1 free base)

Synonym: PTHrP (107–111)

Angiotensin II human TFA

T74142

Synonym:

Target:

RWJ-56110 dihydrochloride

T36717

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
T4S0498	Glaucocalyxin A	Wangzaozin B,Leukamenin F	Apoptosis , Akt , Caspase , PI3K
	1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi...		Apoptosis , Akt , Caspase , PI3K
T2769	3-Aminopropionitrile fumarate (2:1)	Di-β-aminopropionitrile fumarate,3-Aminopropionitrile fumarate,β-Aminopropionitrile fumarate,3-Aminopropionitrile fumarate 2:1,Beta-Aminopropionitrile fumarate,β-Ammoniumpropionitrile hemifumarate	Others
	3-Aminopropionitrile fumarate (2:1) (β-Aminopropionitrile fumarate) is an organic compound and antirheumatic agent used in veterinary medicine.		Others
TN1254	3'-Methoxydaidzein		Sodium Channel
	3'-Methoxydaidzein is a dual isoflavone and Sodium Channel inhibitor. 3'-Methoxydaidzein inhibited NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM and 505 nM, respectively. 3'-Methoxydaidzein was specific for colla...		Sodium Channel
TN6495	3,4-O-dimethylcedrusin
	3′,4-O-Dimethylcedrusin can improve wound healing in vivo by stimulating the formation of fibroblasts and collagen.
TN5661	1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one
	1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one shows strong inhibition of collagen-induced, arachidonic acid-induced, and adenosine diphosphate-induced platelet aggregation of human whole blood.
TN4490	Manassantin B		ERK , BCL , p38 MAPK , TNF , NF-κB , JNK , STAT , Antifection
	Manassantin B is a potent inhibitor of NF-ÎºB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-ÎºB. It also possesses anti-EBV lytic replication activity. Manassantin B inhibits interleu...
T36845	Isogarcinol
	Isogarcinol is a natural polyisoprenylated benzophenone first isolated from plant species in the genus Garcinia. It has immunosuppressant actions, inhibiting the protein phosphatase calcineurin (IC50 = 36 μM) and suppres...
T38330	Collinin
	Collinin is a coumarin that has been found in Z. schinifolium and has diverse biological activities.1,2,3,4 It is active against drug-susceptible and -resistant strains of M. tuberculosis (MIC50s = 3.13-6.25 μg/ml).1 Col...
T35624	Ajoene
	Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs =...

天然物製品

Glaucocalyxin A

T4S0498

Synonym: Wangzaozin B,Leukamenin F

Target: Apoptosis, Akt, Caspase, PI3K

3-Aminopropionitrile fumarate (2:1)

T2769

Synonym: Di-β-aminopropionitrile fumarate,3-Aminopropionitrile fumarate,β-Aminopropionitrile fumarate,3-Aminopropionitrile fumarate 2:1,Beta-Aminopropionitrile fumarate,β-Ammoniumpropionitrile hemifumarate

Target: Sodium Channel

3,4-O-dimethylcedrusin

TN6495

Synonym:

Target:

1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one

Target: ERK, BCL, p38 MAPK, TNF, NF-κB, JNK, STAT, Antifection

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-01132	COL6A3 Protein, Human, Recombinant	Human	HEK293 Cells
	COL6A3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 8.5 kDa and the accession number is D9ZGF2.
TMPY-04164	COL6A3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	COL6A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 11.4 kDa and the accession number is P12111-1.
TMPY-03272	COL4A3 Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	COL4A3 is a major structural component of basement membranes. It is composed of 3 alpha subunits, which are encoded by 6 different genes, alpha 1 through alpha 6. Each of these alpha subunits can form a triple helix s...
TMPH-02591	COL4A3 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.; Tumstatin, a cleavage fragment cor...
TMPH-01121	COL4A3 Protein, Human, Recombinant (His)	Human	E. coli
	COL4A3 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-03266	COL4A3BP Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	COL4A3BP is a member of the StarD2 subfamily. It contains a pleckstrin homology domain at its amino terminus and a START domain towards the end of the molecule. COL4A3BP has a lipid-binding domain that mediates intrac...
TMPJ-00292	CD36 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Platelet Glycoprotein 4 (CD36) is an integral membrane glycoprotein that has multiple physiological functions. It is broadly expressed on a variety of cell types including microvascular endothelium, adipocytes, skeletal ...
TMPJ-00995	Serpin H1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serpin H1 is a serine proteinase inhibitors Which belongs to the serpin family. Serpin H1 is induced by heat shock. Serpin H1 localizes to the endoplasmic reticulum lumen and binds specifically to collagen. Thus it is th...
TMPY-02953	TEM8/ANTXR1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are ser...
TMPH-02934	Thrombospondin-3/THBS3 Protein, Mouse, Recombinant (GST)	Mouse	E. coli
	Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen. Thrombospondin-3/THBS3 Protein, Mouse, Recombinant (GST) is expressed in...
TMPJ-00447	MMP-3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue rem...
TMPY-06986	FGF-8b Protein, Human, Recombinant	Human	E. coli
	In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment...
TMPY-00132	Mesothelin Protein, Human, Recombinant	Human	HEK293 Cells
	Mesothelin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is Q13421-3.
TMPY-05748	CD45 Protein, Human, Recombinant (aa 26-577, His)	Human	HEK293 Cells
	CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3.
TMPY-00357	HNT/NTM Protein, Human, Recombinant (His)	Human	HEK293 Cells
	HNT/NTM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is Q9P121-3.
TMPY-04142	RANK/TNFRSF11A Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	RANK/TNFRSF11A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9Y6Q6-3.
TMPY-04683	CD47 Protein, Human, Recombinant	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-05191	CD47 Protein, Human, Recombinant, Biotinylated	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-03763	Neuropilin-2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Neuropilin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 120.7 kDa and the accession number is O60462-3.
TMPY-01020	Periostin/OSF-2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Periostin/OSF-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is Q15063-3.
TMPY-00892	Neuropilin-2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Neuropilin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 95 kDa and the accession number is O60462-3.
TMPY-01897	PRSS3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains on...
TMPY-01826	Relaxin 1/RLN1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Relaxin-1, also known as Prorelaxin H1 and RLN1, is a secreted protein that belongs to the insulin family. It is a peptide hormone that was first described in 1926 by Frederick Hisaw. Since its discovery as a reproductiv...
TMPY-04298	CDCP1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CDCP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is Q9H5V8-3.
TMPY-00480	NCAM1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	NCAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.1 kDa and the accession number is P13591-3.
TMPY-04935	CD47 Protein, Human, Recombinant (aa 1-139, His)	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is Q08722-3.
TMPY-00072	GITR/TNFRSF18 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	GITR/TNFRSF18 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3.
TMPY-01180	CD86 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3.
TMPJ-01099	IL-15RA Protein, Human, Recombinant (hFc, Human Cells)	Human	HEK293 Cells
	Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bi...
TMPY-02689	MMP-3 Protein, Human, Recombinant	Human	E. coli
	Matrix metallopeptidase 3 (abbreviated as MMP3) is also known as stromelysin 1 and progelatinase. MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular...
TMPK-00447	CD45 Protein, Human, Recombinant (aa 26-577, hFc)	Human	HEK293 Cells
	PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) com...
TMPK-00399	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated	Human	HEK293 Cells
	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
TMPY-04273	FGFR2 Protein, Human, Recombinant (aa 1-378, His)	Human	HEK293 Cells
	FGFR2 Protein, Human, Recombinant (aa 1-378, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41.1 kDa and the accession number is P21802-3.
TMPY-04157	RANK/TNFRSF11A Protein, Human, Recombinant (His)	Human	HEK293 Cells
	RANK/TNFRSF11A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.5 kDa and the accession number is Q9Y6Q6-3.
TMPY-05590	NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 67.9 kDa and the accession number is P13591-3.
TMPJ-00390	FGFR2IIIb Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	FGFR2IIIb Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-90 KDa and the accession number is P21802-3.
TMPJ-00899	HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)	Human	HEK293 Cells
	HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 65 KDa and the accession number is P21860-3.
TMPY-05383	NKp30/NCR3 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	NKp30/NCR3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is O14931-3.
TMPY-03883	CD47 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CD47 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.7 kDa and the accession number is Q08722-3.
TMPY-01656	VEGF183 Protein, Human, Recombinant	Human	Baculovirus Insect Cells
	VEGF183 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 21 kDa and the accession number is P15692-3.
TMPY-06411	GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.79 kDa and the accession number is Q9Y5U5-3.
TMPY-01268	SMYD3 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger...
TMPY-03969	SUSD4 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and ...
TMPY-04386	EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)	Human	Baculovirus Insect Cells
	EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.2 kDa and the accession number is P29323-3.
TMPJ-01288	KLF6 Protein, Human, Recombinant	Human	E. coli
	Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by ...
TMPY-03435	NCKIPSD Protein, Human, Recombinant (GST)	Human	E. coli
	NCKIPSD is localized exclusively in the cell nucleus. It plays a role in signal transduction and may function in the maintenance of sarcomeres and the assembly of myofibrils into sarcomeres. NCKIPSD also plays an importa...
TMPY-00276	PLGF/PGF Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	PLGF/PGF Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 43.7 kDa and the accession number is P49763-3.
TMPJ-00054	PLGF-2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Placental growth factor is a protein that in humans is encoded by the PGF gene. It is a secreted protein and belongs to the PDGF/VEGF growth factor family. Alternate splicing results in at least three human mature PlGF f...
TMPJ-00391	FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)	Human	HEK293 Cells
	FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802-3.
TMPY-05514	RANK/TNFRSF11A Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	RANK/TNFRSF11A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q9Y6Q6-3.
------------------------ More ------------------------